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60 mmHg, Pa CO2 < 50 mmHg, FiO2 < 0.5, PaO2/FiO2 > 200 mg, Tidal volume (VT) > 5 ml/kg, Ve >200 ml/min/kg, PEEP < 5 CmH2O and RR < 45 breath/min.
Weaning failure is defined as the inability to sustain spontaneous breathing without any form of ventilator support, for at least 48 h. The results were tabulated and analyzed with SPSS.
Results:RSBI differed significantly between patients who succeeded weaning from mechanical ventilation and those who failed (3.12±1 vs. 9.5±1.04 breath/min/ml/kg; P < 0.001). A cutoff value ≥3.5 breath/min/ml/kg on were associated with a prediction of failure of weaning from mechanical ventilation with a 100%sensitivity, 75% specificity,0.724 positive predictive value (PPV), 1 negative predictive value (NPV) and 84.91% accuracy.
Conclusion and key messages:Clinical weaning parameter could be considered a sensitive and specific marker for prediction of weaning failure.]]>
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