7%(69.7%) than those with HbA1c<7%(30.3%);(P<0.001). Also complications occurred more significantly in patients with serum triglyceride>150 mg/dl(78.4%) than those with serum triglyceride<150 mg/dl(14%);(P<0.001) and LDL>100mg/dl(82.4) than those with LDL<100mg/dl(15.3%);(P<0.001). Conclusions: There is a significant prevalence of albuminuria in diabetic patients in comparison with non diabetic patients. Complications including life threatening disorder as arrhythmia, heart failure, shock and cardiac arrest occurred more significantly in diabetic albuminuric patients with ACS during admission to ICU. Complications occurred more significantly in patients with abnormal lipid profile especially patients with hypertriglyceridemia or LDL > 100mg/dl]]>
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0.05 then to 112.6+13.8 mg/dl with P<0.001, respectively) (HDL changed from 41.9+ 14 mg/dl to 42.8+15.4 mg /dl, with P<0.05 then to 57.9+23.1 mg/dl to 48.6+25 mg/dl with P<0.001, respectively) Conclusions:We have demonstrated that normal pregnancy is associated with raised triglycerides and cholesterol. By the third trimester most women have a lipid profile which would be considered highly atherogenic in the non-pregnant state. However this represents a transient disturbance which reverts to normal after delivery. Further studies are needed to determine the risk and cardiovascular effects of disturbed lipid profile during pregnancy especially in multipara women with repeated pregnancy.]]>
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0.05). Compared to healthy controls, all patients groups had significantly decreased total and five index RBANS scores [the repeatable pattery for assessment of neuropsychological status] (all P < 0.01 – P < 0.001), except for the visuospatial/ constructional index. SZ with diabetes performed worse than SZ without diabetes in immediate memory (P > 0.01) and total RBANS scores (P < 0.05) and showed a trend for decreased attention (P = 0.052) and visuospatial/constructional capacity (P = 0.63). SZ with diabetes performed worse than diabetes only in immediate memory (P < 0.001) and attention (P < 0.05) and showed a trend for decreased total RBANS scores (P = 0.069). Conclusion and Recommendations: SZ with Co-morbid diabetes showed more impairment than SZ without diabetes or diabetes only especially in immediate memory & attention. Thus, diabetes prevention and control should be targeted in patients with SZ.]]>
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0.01) and relative risk each of ascites (1.3fold),intractable ascites (9.5fold), spontaneous bacterial peritonitis (2.6fold), hepatic hydrothorax (1.5fold) and hepatic encephalopathy (2.8fold), in hyponatremic groups compared to normonatremic one while there was no significant difference regarding hepatorenal syndrome, esophageal varices and variceal bleeding between different groups. Also there was a statistically significant negative correlation betwee serum sodium level and the two scoring systems: Child-Pugh score (r =-0.690, p<0.001) and Model for End – stage Liver Disease (MELD) score(r =-0.586, p<0.001 ).We can conclude that In critically ill patients with liver cirrhosis, the prevalence of total hyponatremia(Na ≤ 135 meq/L) was 65.5% while those with severe hyponatremia (Na ≤130) was 45.5%. Low serum sodium level was associated with high complications of liver cirrhosis. The relative risk of occurance, frequencies and severity of ascitis, intractable ascitis, hepatic hydrothorax, hepatic encephalopathy and spontineous bacterial peritonitis were increased in cirrhotic patients especially those with serum sodium levels ≤ 130 meq/L.So the Management of hyponatremia may decrease the incidence and severity of the liver cirrhosis complications with better quality of their life. Thus more interest should be tried towards the use of vasopressin receptor antagonists as a line of treatment of complicated cirrhotic patients with hyponatremia without salt overload]]>
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2.0 mm in diameter, and/or patients undergoing double vessel PCI. Exclusion criteria; Patients with heart failure and lesions > 30 mm in length, patients with high syntax high syntax score, Patients with coronary bypass grafts, previous PCI and patients with instent restenosis. PPI was defined as troponin T elevation (N 0.1 ng/mL) at 6–24 h post-PCI. Results: Patients were classified according to presence or absence of diabetes mellitus (DM) into two groups; group I (non-diabetic patients DM; 33 patients, 23 males, 10 females, their age ranged from 42- 62 years with mean 50.2±5.3 years), group II (diabetic patients; 27 patients, 16 males, 11 females, their age ranged from 45 -65 years with mean age of 54.4±5.4 years). Patients were reclassified according to syntax score into two groups; group A (with low score (0-22); 48 patients) & group B (with intermediate score (22-32); 12 patients).The mean patient SXscore was higher in diabetic patients and non diabetic patients (22.6 vs. 12.4, p = 0.0001), Gensini score was significantly higher in diabetic patients (52.4 vs. 25.3, p = 0.15). Also mean PCI vessel SXscore was higher in vessels associated with PPI (12.1 vs. 7.6, p = 0.002), but not different for PCI vessel Gensini score (16.2 vs. 13.6, p = 0.42). No vessels with AHA type A lesions were associated with PPI. Higher AHA classification (B and C) were associated with PPI. In total, 60 patients undergoing PCI to 77 vessels were included in the analysis, There were 43/60 (71.6%) patients who had myocardial injury. The incidence of PPI among diabetic patients was higher than non diabetic patients (24/27, 88.9% vs 19/33, 57.6% respectively) reflecting procedural complexity, (long lesion and total occlusion) more in diabetic patients. Indeed, the procedural complexity reflected by the mean patient SXscore was higher in the diabetic patients group than non diabetic patients undergoing day case PCI. By ROC analysis, we found that a patient with high SXscore of ≥ 15 can be considered as predictor of PPI with a sensitivity of 95.3% and specificity of 88.2%.Conclusion: Higher SXscores are predictive of myocardial injury, whilst AHA type A lesions have a high negative predictive value for PPI.]]>
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0.05). The spearman correlation analysis revealed a significant positive association between BMI1 and EZH2 expressions (r = 0.311; P=0.05) revealing direct relationship between BMI1 and EZH2.Conclusions: BMI1 and EZH2 were involved in astrocytoma malignant transformation and poor prognosis in astrocytoma particularly glioblastoma.]]>
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