Intralesional Injection of Bleomycin In The Treatment of Keloids

Document Type : Original Article

Authors

1 Dermatology, Venereology and Andrology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt

2 Dermatology, Venereology and Andrology Department, faculty of Medicine, Zagazig University,Zagazig, Egypt

3 Dermatology, Venereology and Andrology department, Belbeis central hospital, Al-sharkia, Egypt.

Abstract

Background: Keloid is a common clinical distressing problem. Its treatment is a challenging process due to its high rate of recurrence and resistance to some therapies. The aim of this study is to evaluate the efficacy and safety of intralesional injection of bleomycin in the treatment of keloids.
Subject and Methods: Ten patients with keloid lesions were included in this study. Patients were injected every 2 weeks for 6 sessions using intralesional injection of bleomycin at a concentration of 1.5 IU/ml in normal saline solution with a maximum dose of 6 ml per session.
Results: The results were satisfying as percentage of improvement after treatment was 60% according to Vancouver score and was (80% & 87.5%) according to pain and pruritus scores respectively.
Conclusion: Intralesional injection of bleomycin is an effective and safe modality in the treatment of keloids.
Key words: Keloid, Intralesional, Bleomycin.
Corresponding Author: Wesam Khaled Mohamed Emam,
Wesamkhaled88@Gmail.com,01111328143.

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