Trabeculectomy with Ologen combined with Mitomycin-C for the management of Primary Congenital Glaucoma

Document Type : Original Article

Authors

1 Ophthalmology department , Faculty of medicine, Zagazig university, Zagazig, Egypt

2 Department of Ophthalmology Zagazig university Zagazig Egypt

Abstract

Background: Ologen is a collagen matrix designed to promote wound healing with minimal scarring. It has been used to create a prominent and healthy vascular bleb following trabeculectomy.
Aim: The purpose of this study is to evaluate the adjunctive use of Ologen with mitomycin-C augmented trabeculectomy in eyes with primary congenital glaucoma.
Patients and Methods: Ologen was placed in the subconjunctival space and under the scleral flap in 25 eyes of 21 patients with primary congenital glaucoma who underwent trabeculectomy with Mitomycin-C. Patients were examined preoperatively and in the 1st week, 1st, 3rd, 6th and 12th months after surgery. Examination included measurements of the intraocular pressure, corneal diameter, bleb evaluation, and fundus examination. Ultrasound biomicroscopy of the bleb was done at the last follow-up visit.
Results: The mean age of the patients was 6.6 ± 2.95 months. Mean preoperative IOP was 22.56 ± 0.83 mmHg and the mean final postoperative IOP was 15.52 ± 3.54 mmHg. Complete success (IOP

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Zagazig University Medical Journal
Volume 29, Issue 3
May and June 2023
Pages 942-948

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