Comparison Between Gadolinium Enhanced Susceptibility Weighted Imaging And Conventional T1-Weighted Imaging In Optimizing The Recognition Of Active Plaques Of Multiple Sclerosis

Alsowey, Ahmed Mohamed; Rady, Sara Mohamed; Abdelrahman, HossamEldin Mansour; Elsayed, Heba Abdelmonem

doi:10.21608/zumj.2021.95908.2347

Comparison Between Gadolinium Enhanced Susceptibility Weighted Imaging And Conventional T1-Weighted Imaging In Optimizing The Recognition Of Active Plaques Of Multiple Sclerosis

Document Type : Original Article

Authors

¹ Radiodiagnosis Department; Faculty of medicine, Zagazig University, Egypt.

² Radiodiagnosis department, Faculty of medicine, Zagazig university, Zagazig, Egypt.

³ Radiodiagnosis Department , Faculty of medicine, Zagazig University, Zagazig, Egypt.

⁴ Radiodiagnosis Department, Faculty of medicine, Zagazig university, Zagazig Egypt.

10.21608/zumj.2021.95908.2347

Abstract

Background: The Gd-SWI sequence is a new important magnetic resonance imaging sequence that has been applied currently due to its ability to optimize the recognition of active plaques of MS and has a higher accurate performance than gadolinium T1WI that is currently used in clinical practice.
Aim: comparing the performance of the Gd-SWI sequence with the performance of other used sequences in clinical practice in detection of blood brain barrier (BBB) dysfunctions in MS plaques.
Methods: in this retrospective study, Twenty four patients were involved (16 females and 8males, their age ranging from 20- 42 years with the mean age 26.33 years), they were divided into two groups: 8 active cases and 22 inactive cases clinically and radiologically proven MS cases for MRI diagnosis and follow up.
Results: Two thirds of the studied group (66.7 %) had inactive lesions and one third (33.3 %) had active ones with (12.5 %) of both active and inactive lesions were progressive. There was higher ability of post-contrast SWI to demonstrate active plaques than post-contrast TIWI and there was highly statistically significance and good agreement (kappa=0.71) with 89.5% percent of agreement between post contrast enhanced lesions by SWI and T1 and statistically highly significant difference (p < 0.001).
Conclusions: Gadolinium –SWI technique improved detection accuracy of MS- contrast-enhanced plaques better than Gd-T1 SE, including their locations and morphologies.

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