Potential Therapeutic Effect of Platelet Rich Plasma In Acne Vulgaris

Document Type : Original Article

Authors

1 Dermatology,venereology and andrology department, zagazig university, Zagazig, Egypt

2 Dermatology, Andrology and Venereology department, Faculty of Medicine, Zagazig University, Egypt

Abstract

Background: Acne vulgaris is a worldwide chronic inflammatory dermatological disorder of pilosebaceous unit that adversely affects patients’ quality of life, so safe and effective treatment options are needed. Platelet rich plasma is an autologous highly concentrated platelets in a little amount of plasma. Various growth factors are released after platelet activation that have significant role in angiogenesis, inflammation and wound healing.

Aim of Study: To assess the efficacy and safety of platelet rich plasma injection in management of acne vulgaris.
Patients and Methods:
Thirty patients with acne vulgaris of different severity and duration received four sessions of platelet rich plasma that injected intradermally, one session every two weeks for 8 weeks.
Results:
The obtained results showed a statistically significant decrease in the total lesion count (P

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Zagazig University Medical Journal
Volume 30, Issue 1.2
January and February 2024
Pages 336-341

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