Neutrophil to Lymphocyte Ratio as a Predictor for Spontaneous Bacterial Peritonitis in Patients with Cirrhotic Ascites

Document Type : Original Article

Authors

1 Department of Internal Medicine, Al Zawia University, Libya

2 Internal medicine,faculty of medicine,zagazig university,Egypt

3 Department of Internal Medicine, Zagazig University , Egypt

4 Department of Internal Medicine, Zagazig University , Egypt.

Abstract

Background: The most prevalent infection in cirrhotic individuals is spontaneous bacterial peritonitis (SBP). Acute GI bleeding, a history of SBP, or low ascetic fluid protein contents are all risk factors for the development of SBP in cirrhotic individuals. The purpose of this study was to see if the neutrophil-to-lymphocyte ratio (NLR) could predict spontaneous bacterial peritonitis in individuals with liver cirrhosis. Patients and methods: This prospective, case-control and observational study was conducted at Internal Medicine Department, Zigzag University Hospitals during the period from June 2021 to March 2022. The study included 100 cirrhotic patients. The patients were divided into two groups: Group I included 50 cirrhotic patients with SBP (case group) and group II included 50 cirrhotic patients without SBP (control group). Neutrophil to lymphocyte ratio was calculated for all patients. Results: In this study, there was statistically significant difference between the two studied groups in neutrophil count, lymphocyte count and increased neutrophil to lymphocyte ratio (group 1 had increased neutrophils and decreased lymphocytes than group 2). Conclusion: We can conclude the clinical utility of NLR as a biomarker predictive factor in the occurrence of spontaneous bacterial peritonitis (SBP) .

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Zagazig University Medical Journal
Volume 28, Issue 6.2
supplement 2
November 2022
Pages 365-373

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