Portal Hypertensive Gastropathy and Severity of Liver Disease in Patients with Liver Cirrhosis

Document Type : Original Article

Authors

1 Department of Hepatology and Gastroenterology and infectious Diseases. • Benha Teaching Hospital

2 lecturer of hepatology benha faculty of medicine

Abstract

Abstract:

Background and study aim:
In individuals with liver cirrhosis, portal hypertensive gastropathy (PHG) is a complication of portal hypertension and one of the leading causes of gastrointestinal bleeding.
The modified Child's score (CTP) and the Model for end stage liver disease (MELD) score are used to determine the severity of liver disease in cirrhotic patients.
The goal of this study is to see if there's a link between PHG and the severity of liver disease.
METHODS: 300 patients with chronic liver disease were enrolled in the trial. The degree of liver disease was determined in all patients using the (CTP) and MELD scores. Varices and PHG were discovered during an upper gastrointestinal endoscopy.
RESULTS: The number of patients evaluated was 300, with 72% of them being men and a median age of 60 (45-66) years. Child's score revealed that 38% were Child B, 32% Child A, and 30% were Child C, with a median MELD score of 13 (11-18). During an upper endoscopy, it was discovered that 50% of the patients had significant esophageal varices, and 72% had severe PHG. PHG was substantially related with esophageal and fundal varices (P = < 0.001,0.005), respectively. presence and severity of PHG were both positively correlated with the severity of chronic liver disease, measured by MELD, Child's score (P = < 0.001).
CONCLUSION: presence and severity of portal hypertensive gastropathy (PHG) are linked to severity of liver disease measured by CTP and MELD scores.

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Zagazig University Medical Journal
Volume 29, Issue 3
May and June 2023
Pages 949-953

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