Clinical characterization, imaging and response to treatment in a sample of Egyptian patients with idiopathic intracranial hypertension

Document Type : Original Article

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Department of Neurology, Faculty of Medicine, Zagazig University, Egypt

Abstract

Background: Increased intracranial pressure with normal brain parenchyma and no evidence of a secondary cause, such as a mass lesion or hydrocephalic alterations, is known as idiopathic intracranial hypertension (IIH). Aim: This study objective was to examine the clinical manifestation and therapeutic response in a cohort of adult patients. Patient and methods: The Neurology Department of Zagazig University Hospitals conducted our prospective cohort study from March 2022 to February 2023. eighteen patients with idiopathic intracranial hypertension participated in the study (15 females and 3 males).Their age range from 19-42 year with a mean age (±SD) of 30.6 (± 6.2).A thorough neurological and ophthalmological examination was performed, including tests for contrast sensitivity, colour vision, assessment of visual acuity (VA) and visual field. After three months, follow-up was conducted. Results: IIH was more prevalent among obese females. Headache with blurring of vision without nausea or vomiting was the most important symptom. Papilledema was the obvious sign for diagnosis.Treatment had significant improvement regarding headache and degree of papilledema and can be used as predictor for improvement. Conclusion: In this study we found that clinical assessment of headache severity and papilledema grade are important findings in evaluating improvement in patients with IIH.

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Zagazig University Medical Journal
Volume 30, Issue 3
May and June 2024
Pages 897-904

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