Effects of Propofol Versus Sevoflurane on Recovery outcome for outpatient Surgery in Pediatrics

Soliman, Hosam Mohamed; Ahmed El-Hossary, Zeinab Ibrahim; Abd Alsalam AlKhazimi, Mustafa Othman; Nazmi Mohammed, Hatem Ahmed

doi:10.21608/zumj.2023.226192.2834

Effects of Propofol Versus Sevoflurane on Recovery outcome for outpatient Surgery in Pediatrics

Document Type : Original Article

Authors

¹ Department of Anesthesia, Intensive Care and Pain management, Faculty of Medicine, Zagazig University, Egypt

² Intensive Care and Pain Management, Faculty of Medicine- Tripoli university - Libya

10.21608/zumj.2023.226192.2834

Abstract

Background: The most often used anesthetics for pediatric surgery are propofol and sevoflurane. These general anesthetics' main side effects are postoperative discomfort, nausea and vomiting, and agitation during the recovery room. The safety of sevoflurane and propofol in pediatric surgery has been compared in numerous clinical investigations, although the findings were unclear. So, this study aimed to compare effective outpatient surgery in pediatrics with reducing emergence agitation, delirium, and anesthesia complications by comparing effects Propofol or sevoflurane on recovery outcome for outpatient surgery in pediatrics. Patients and Methods: This Randomized, double-blind clinical study was conducted on 40 cases planned for outpatient surgery in pediatrics attended the anesthesia, intensive care, and pain management department in Zagazig University Hospitals throughout six months started from March 2023 to September 2023. All Cases were chosen from Zagazig University Hospitals' outpatient clinics who were willing to have an elective outpatient surgery. Results: There was significant shorter extubation time and discharge time in the Propofol group compared to Sevoflurane group. Otherwise there were no significant differences between groups regards other parameters. There was significantly lower heart rate in the Propofol group from basal reading until 45 minute of operation time compared to Sevoflurane group. Conclusion: When compared to sevoflurane anesthesia, children who underwent propofol anesthesia had lower chances of emerging anxiety, postoperative nausea and vomiting, and postoperative discomfort. In comparison to sevoflurane-based anesthetic, the propofol regimen provided a more relaxing recovery and reduced postoperative respiratory problems in infants undergoing outpatient surgery.

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