The Role of Selenium Deficiency In Dilated Cardiomyopathy

Document Type : Original Article

Authors

1 pediatric department,faculty of medicine ,zagazig university,elsharkia,Egypt

2 pediatric departement, faculty of medecine,zagazig university,Elsharkia,Egypt

3 departement of pediatric ,faculty of medicine ,zagazig university,elsharkia,Egypt

4 clinical pathology,faculty of medecine,zagazig university,elshakia,Egypt

Abstract

ABSTRACT:
BACKGROUND:
It has been speculated that trace elements may play a role in the pathogenesis of dilated cardiomyopathy (DCM). In the present study, we aimed to assess serum concentrations of selenium (Se) in pediatric patients with idiopathic dilated cardiomyopathy (IDC) and to evaluate the correlation between serum Se concentrations and echocardiographic parameters.
SUBJECTS AND METHODS:
This study included 16 patients with IDC and 16 healthy controls. Serum level of selenium was measured by ELIZA method. Echocardiographic parameters including ejection fraction and fractional shortening were measured in all patients with IDC in order to evaluate its correlation with serum Se concentrations.
RESULTS:
Serum concentration of Se in IDC patients was significantly lower than in healthy controls (p

Keywords

Zagazig University Medical Journal
Volume 26, Issue 1 - Serial Number 1
Medicine - Pediatrics - Laboratory Medicine
January and February 2020
Pages 46-52

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