Background: Study of expression of lymphocyte subsets could help to understand the pathophysiology of COVID-19 infection, development of novel treatment protocols and reducing rate of mortality among COVID-19 infected patients.
Objective: The aim of this work was to correlate expression of lymphocyte subsets with the inflammatory markers and clinical status of patients with COVID-19 infection.
Patients and methods: This prospective study was performed at Zagazig University Isolation Hospitals and clinical pathology department, Zagazig, Egypt on 80 persons who were enrolled in this study; 40 COVID-19 patients with pneumonia made up group I, and the following individuals made up group II: 40 COVID-19 patients without pneumonia. Immunophenotyping of CD4 CD8 were measured by Flow Cytometry in both groups.
Results: Patients had a considerable drop in CD4 CD8 levels with pneumonia than those without pneumonia
Conclusion: Low levels of CD4 CD8 in COVID-19 patients are associated with a higher risk of pneumonia.
Meshref Esmail, A., Baraka, A., Hassan, T., & Ahmed, A. (2023). Lymphocyte Subsets Expression of CD4 and CD8 in COVID-19 Infected Patients. Zagazig University Medical Journal, (), -. doi: 10.21608/zumj.2023.234175.2872
MLA
Alaa Husseiny Meshref Esmail; Ahmed Mohamed Baraka; Tarek Hamdy Hassan; Ahmed Mokhtar Ahmed. "Lymphocyte Subsets Expression of CD4 and CD8 in COVID-19 Infected Patients". Zagazig University Medical Journal, , , 2023, -. doi: 10.21608/zumj.2023.234175.2872
HARVARD
Meshref Esmail, A., Baraka, A., Hassan, T., Ahmed, A. (2023). 'Lymphocyte Subsets Expression of CD4 and CD8 in COVID-19 Infected Patients', Zagazig University Medical Journal, (), pp. -. doi: 10.21608/zumj.2023.234175.2872
VANCOUVER
Meshref Esmail, A., Baraka, A., Hassan, T., Ahmed, A. Lymphocyte Subsets Expression of CD4 and CD8 in COVID-19 Infected Patients. Zagazig University Medical Journal, 2023; (): -. doi: 10.21608/zumj.2023.234175.2872
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