Is There an Association between Thyroid Disease and Metabolic Syndrome

SAEID, AHMED KHAMEES; Salem, Hatem M.; Enaba, Moanes; Ghanem, Nermin Saad

doi:10.21608/zumj.2023.249581.3008

Is There an Association between Thyroid Disease and Metabolic Syndrome

Document Type : Review Articles

Authors

¹ Faculty of Medicine, Tobruk university

² Professor of Internal Medicine, Zagazig University.

³ Radiodiagnosis Department, Faculty of Medicine, Zagazig, Egypt

⁴ Internal Medicine Department, Faculty of Medicine, Zagazig University, Egypt

10.21608/zumj.2023.249581.3008

Abstract

Background: The metabolic syndrome and thyroid dysfunctions are the two most prevalent endocrine illnesses, and they significantly overlap. Due to their strong associations with morbidity and mortality, both have a huge global influence on health care. Insulin resistance (IR) is a primary component of metabolic syndrome (MetS), a collection of disorders related to metabolism. The management and maintenance of cellular energy balance depend on thyroid hormones (TH). Both the central nervous system and TH's direct connection with peripheral target organs serve as mediating mechanisms for these activities. Recently, there has been discussion on the potential link between MetS and its constituent parts and changes in the morphology and function of the thyroid gland. Studies concentrating on TNs' risk factors are required because of the disease's significant morbidity.

Aim: To summarize recent developments in the association of thyroid function with metabolic syndrome (MetS).

Conclusion: Thyroid stimulating hormone, free T3, free T4, and metabolic parameters have a complex relationship that may be influenced by inflammatory markers, age, sex, BMI, insulin resistance, smoking, iodine intake, and other factors.

Keywords

Main Subjects