Possible correlations between Acute coronary syndrome and Diabetes Mellitus: Review Article

Document Type : Review Articles

Authors

1 Cardiology Department, Faculty of Medicine-Zagazig University

2 Cardiology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt

Abstract

Background: Hyperglycemia and glucose intolerance are hallmarks of diabetes mellitus, an illness that can arise from insulin insufficiency, decreased insulin action, or both. Coronary artery disease (CHD) account for most health-care costs in diabetic people. T2DM is closely linked to CHD. Several investigations have demonstrated this strong association. The risk of cerebrovascular disease and stroke is increased by having diabetes. There are a number of macrovascular problems associated with type 2 diabetes, including an increased risk of death, ischemic disease, stroke, and other cardiovascular events. Conditions such as unstable angina, ST-elevation myocardial infarction (STEMI), and non-ST elevation myocardial infarction (NSTEMI) are all part of acute coronary syndrome (ACS). It is a subtype of CHD that accounts for one-third of all fatalities in adults over the age of 35. The present evidence regarding the Possible correlations between Acute coronary syndrome and Diabetes is summarized in this review.

Conclusion: With a high death rate and a growing frequency over the past decade, diabetes is a common comorbidity among patients hospitalized for acute coronary syndromes (ACS). Diabetic individuals make up about 25-30% of ACS admissions. Diabetics are more likely to experience ACS, which happens earlier in the disease and is linked to higher mortality and the likelihood of further ischemic episodes. The worse outcomes seen by diabetic individuals are accompanied by an elevated proinflammatory and prothrombotic condition.

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Zagazig University Medical Journal

Articles in Press, Accepted Manuscript
Available Online from 27 February 2024

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