Role of Diffusion Weighted Imaging & Dynamic Contrast Enhanced Magnetic Resonance Imaging in Assessment of Asymmetric Breast Densities

Document Type : Original Article

Authors

1 Department of Radiodiagnosis, Faculty of Medicine, Zagazig University, Zagazig, Egypt

2 Radio diagnosis Department, Faculty of Medicine, Zagazig University

Abstract

Abstract Objective: The aim of the study is to determine the diagnostic value of both DCE-MRI & DW-MRI in assessment of cases with mammographic asymmetrical breast densities.
Methods: This study was carried out at Radiodiagnosis Department, Zagazig University Hospitals, on 29 patients with breast asymmetry. Diagnostic work up included Mammography, US, & MRI.
Results: The study included 29 females with mammographic breast asymmetry, 17 were having global asymmetry, while 12 with focal asymmetry.65.52% of asymmetry in this study was due to benign causes while 34.48% was due to malignant causes, DCE-MRI provided special characterization of lesions by their morphology & dynamic enhancement with 90% sensitivity 84.21% specificity, & 86.2% accuracy. DWI & ADC value provided differentiation between malignant & benign lesions, malignant lesions showed restricted diffusion with lower ADC values than benign lesions, the mean ADC value for benign lesions was (1.4±0.45x10-3sec/mm2), & the mean ADC value for malignant lesions was (0.85±0.29x10-3sec/mm2), & the cutoff ADC value was (

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