Lipid Profile Disorder among patients with type 2 diabetes mellitus.

Document Type : Original Article

Authors

1 Internal Medicine Department, Faculty of Medicine, Zagazig University, Sharkia Egypt

2 Family Medicine department, Faculty of Medicine, Zagazig university, Egypt

3 Resident of Family Medicine, South Sinai directorate of health, Ministry of health, Egypt

Abstract

Background
Type 2 diabetes mellitus (T2DM) is a notable disease in developing and/or developed countries associated with a high risk of morbidity form cardiac disease. It has been proposed that the composition of lipid particles in diabetic dyslipidemia is more atherogenic than other types of dyslipidemia. The aim of our study was to identify the relation between T2DM and the lipid profile disorders and identify the factors associated with increasing the risk of dyslipidemia in patients with T2DM.
Method:
We conducted an epidemiological cross-sectional study in DM Clinic in comprehensive health insurance clinic Tur Sinai District in Egypt. We included patients with T2DM, patient age from 18 to 60 years old, and apparently uncomplicated.
Results:
We enrolled 94 patients with T2DM with mean age of 49.5 ± 9.12 years. Of whom, 42 (44.7%) were male and 52 (55.3%) were females. About 55% of the studied patients had dyslipidemia. On assessing each item in lipid profile, (53.2%) of the studied patients had abnormally high triglycerides level, 46.9% of them had hypercholesterolemia, 45.9% had abnormal LDL-cholesterol level and 25.5% of them had low HDL level. Fasting blood glucose and glycosylated hemoglobin were significantly higher among DM patients with dyslipidemia.
Conclusions:
This study highlighted high prevalence of dyslipidemia associated with DM. The present study also highlights the importance of strict control of DM in prevention and treatment of dyslipidemia as dyslipidemia is more frequent in uncontrolled diabetic patients and decreasing BMI and absence of hypertension can protect against the risk of dyslipidemia

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