Office Hysteroscopy and Pipelle Endometrial Biopsy versus Diltation and Curettage in Diagnosis of Endometrial pathology in women with perimenopausal bleeding.

Abd-Elmageed, Ahmed Abd-Elwahed; Abdo, Ahmed; El Beheidy, Tarek Mohamed; Refaie, Ashraf Nasr

doi:10.21608/zumj.2019.15285.1371

Office Hysteroscopy and Pipelle Endometrial Biopsy versus Diltation and Curettage in Diagnosis of Endometrial pathology in women with perimenopausal bleeding.

Document Type : Original Article

Authors

¹ obstetrics and gynacology department,faculty of medicine,zagazig univercity,Sharkia,Egypt

² Zagazig university

³ obstetric and gynecology department zagazig university hospitals

⁴ zagazig university

10.21608/zumj.2019.15285.1371

Abstract

Background: Abnormal uterine bleeding(AUB) is a common gynecologic complaint. Some authors recommend endometrial sample in diagnosing AUB by pipelle method and hysteroscopy. However, this need more investigations to be proven.
The aim of the study: Was to compare between the histopathological findings of Pipelle endometrial biopsy, office hysteroscopy and dilatation and curettage(D&C) (the gold standard).
Patients & methods: This cross-sectional study was carried out in outpatient clinic of Obstetrics & Gynecology Department at Zagazig University Hospitals, Zagazig, Sharkia, Egypt, from July 2018 till March 2019. Fourty three cases were included. All women were present with perimenopausal bleeding. Full history was taken, office hysteroscopy was done, pipelle endometrial aspiration after 2 hours , D&C within 48 hours then tissue samples were placed into bottles containing formalin 10% and sent for histopathological examination and finally the results were compared.
Results: Histopathological examination of endometrial samplings by pipelle method revealed endometrial hyperplasia in 10 cases , hyperplasia with atypia in 4 cases, polyp in 0 cases, endometritis in 3 cases.Also, hysteroscopy revealed endometrial hyperplasia in 8 cases , hyperplasia with atypia in 2 cases, polyp in 5 cases, endometritis in 2 cases.These were correlated with histopathological findings of conventional D and C sampling method which showed that endometrial sampling by pipelle method and hysteroscopy had a high sensitivity and spesificity in diagnosing abnormal endometrium.
Conclusion: Pipelle endometrial sampling and hysteroscopy are an easy and safe methods of tissue diagnosis which can be done as an out-patient procedures and without anaesthesia.

Keywords

Main Subjects