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0.05). Total antioxidant levels of patient and controls were 0.99 ± 0.243 mM/L and 1.088±0.283 mM/L, respectively (P>0.05) non-significant.Conclusion: The role of antioxidant enzymes in the protection against senile cataract formation is still controversial. As the result of this study, glutathione peroxidase enzyme is found to be the most important enzyme over the other antioxidants as a strong correlation was found between the low levels of GPx in erythrocytes and the development of senile cataract. However large multi-center studies are required before establish this concept.]]>
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50%, G2 with EF<50%. They were fatherly divided according to positive family history (FH) of DM; G1a with -ve FH, G1b with +ve FH, G2a with –ve FH, G2b with +ve FH. We searched for IR by measuring HOMA-IR and measured fasting Blood sugar (FBS) and HbA1c as markers of glycaemia. Coronary angiography was done and severity of coronary artery disease was calculated by Gensini score.Results: In our study we discovered a cutoff point = 5.5% for HbA1c to predict the systolic heart failure. It showed a good specificity and fair sensitivity (73.5%, 43.9%) respectively. There was a highly statistical significant difference between HbA1c and number of coronary arteries affected (X = 9.7, p =0.004). As regard HbA1c and Gensini score, there was a highly statistical significant difference (X = 10.5, p =0.001). We also discovered a cutoff point = 1.9 for HOMA-IR to predict the systolic heart failure in our study. There was a significant relation between Gensini Score and dyslipidemia(r =0.337, p= 0.001), hypertension (r = 0.255, p = 0.011) and fasting blood sugar (r = 0.229, p = 0.022). There was also a significant correlation between systolic heart failure and dyslipidemia (r =0.315, p= 0.001) and hypertension (r = 0.251, p = 0.012) in non-diabetic patients.Conclusions: We conclude that in non-diabetic patients with CAD, HbA1c above the cutoff point 5.5% can predict an increasing severity of the coronary artery disease and the number of the affected coronary arteries.]]>
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