@article { author = {Zeid, Nabil and Mohammed, Ahmed and El-Fouly, Mahmoud and El-Essawy, Mahmoud}, title = {THE RELATIONSHIP BETWEEN SYSTEMIC STEROID THERAPY AND THE LEVEL OF SERUM IGE IN ALLERGIC FUNGAL RHINOSINUSITIS}, journal = {Zagazig University Medical Journal}, volume = {22}, number = {5}, pages = {1-8}, year = {2016}, publisher = {Zagazig University, Faculty of Medicine}, issn = {1110-1431}, eissn = {2357-0717}, doi = {10.21608/zumj.2016.4665}, abstract = {Background: Adequate study of allergic fungal rhinosinusitis (AFRS) helped better understanding of the nature of the disease. It involves immediate hypersensitivity to fungus present in the nose and sinuses. This involves immunoglobulin E. Therefore the presence of serum IgE indicates the presence of the allergic reaction.The objective is to evaluate the relationship between systemic steroid therapy and the level of serum IgE in allergic fungal rhinosinusitis indicating adequate therapy. This is a prospective study.Subjects and Methods: Forty patients diagnosed as allergic fungal sinusitis were randomly divided into two equal groups: group A was given postoperative systemic steroids and local steroids, while group B was not given systemic steroids (local steroids only). The patients were followed up for three and six months by testing IgE levels in blood.Results: The total number of patients who had more than 10% increase in serum IgE after 6 months post-operative was 18 patients. Six of them were from group A (Systemic steroids) and 12 were from group B (Local steroids).Conclusion: There was a strong relation between systemic steroid therapy and the level of serum IgE. Thus, AFS should be treated by systemic steroids for a prolonged period after adequate clearance of the sinuses. Patients should be followed up at close intervals post-operative using serum Ig E as it can indicate increased fungal load and the need for further treatment.}, keywords = {Allergic,FUNGAL,sinusitis,Ig E,steroids}, url = {https://zumj.journals.ekb.eg/article_4665.html}, eprint = {https://zumj.journals.ekb.eg/article_4665_566b1972586e3f994a88fb7845adee8c.pdf} } @article { author = {Bahaa El-Din, Rasha and El-Badawy, Amal and Khafajy, Ghada}, title = {EFFECT OF MOTIVATIONAL INTERVIEWING IN IMPROVEMENT OF DIABETIC KNOWLEDGE of TYPE 2 DIABETIC PATIENTS IN Zagazig UNNIVERSITY HOSPITAL, A RANDOMIZED CONTROL TRIAL}, journal = {Zagazig University Medical Journal}, volume = {22}, number = {5}, pages = {1-9}, year = {2016}, publisher = {Zagazig University, Faculty of Medicine}, issn = {1110-1431}, eissn = {2357-0717}, doi = {10.21608/zumj.2016.4666}, abstract = {Background: Type 2 diabetes (T2D) incidence has increased rapidly globally during the last two decades. Lifestyle and behavioral factors such as diet, exercise and self-care have an essential role in the prevention and management of T2D. The motivation behind the desire to change is a cornerstone of adopting a healthier lifestyle. Motivational interviewing (MI) is a counseling technique that helps individuals to change rather than just give information.Methodology: One stage randomized controlled trial to assess the effect of the motivational interviewing intervention. A sample of (210) type 2 diabetic patients were drawn randomly from the diabetes outpatient clinic in Zagazig University Hospital. The patients were randomly allocated into the interventional (105) group who received education using MI counseling, and the control (105) group who received usual medical advice. The patients were assessed from baseline and after 3 months as regard general diabetic Knowledge.Results: The motivational interview significantly improved the general diabetic knowledge in the interventional group compared to the control group (p<0.001) after 3 months follow-up.Conclusion: MI has positive effect in improvement of general diabetic knowledge in type 2 diabetic patients.}, keywords = {Motivational Interviewing (MI),Type 2 Diabetes,Knowledge,health education,Zagazig}, url = {https://zumj.journals.ekb.eg/article_4666.html}, eprint = {https://zumj.journals.ekb.eg/article_4666_37ca831a08ab23fc2c8326c29586aa10.pdf} } @article { author = {Alyan, Ahmed and Aswad, Mahmoud and Dabour, Sherif and Hanefa, Hassan}, title = {PROGNOSTIC FACTORS FOR PREDICTING VISUAL OUTCOME AFTER VITRECTOMY FOR POSTERIOR SEGMENT INTRAOCULAR FOREIGN BODIES}, journal = {Zagazig University Medical Journal}, volume = {22}, number = {5}, pages = {1-9}, year = {2016}, publisher = {Zagazig University, Faculty of Medicine}, issn = {1110-1431}, eissn = {2357-0717}, doi = {10.21608/zumj.2016.4667}, abstract = {AIM: To analyze the prognostic factors and assess the visual outcome in patients with IOFBs treated by pars plana vitrectomy.PATIENTS AND METHODS: This study was a prospective interventional case series of 80 consecutive eyes of patients with penetrating eye injuries and retained intraocular foreign body (IOFB) in the posterior segment who underwent IOFB removal by pars plana vitrectomy at Zagazig University Hospitals between August 2013 and December 2015. Three different groups were categorized according to final BCVA. Various preoperative, operative, and postoperative Factors were analyzed for their prognostic value for a good visual outcome and a poor visual outcome.RESULTS: There were 74 males and 6 females with a mean age of 28.80±7.82 years. Hammering and chiseling were the most frequent source of injury occurred in 69 patients (86.25 %). Final best corrected visual acuity (BCVA) was equivalent to or more than 0.5 (good outcome) in 28 patients, between 0.1–0.4 in 20 patients and less than 0.1 (poor outcome) in 32 patients. Age, sex of patients and preoperative retinal detachment (RD) were statistically insignificant for visual outcome. Initial poor BCVA was found to be highly significant for poor final BCVA (p<0.001). Corneoscleral entry site and intraretinal FB location were found to be highly significant for poor visual outcome (p<0.001). Corneal entry site and IOFBs finally located in vitreous cavity were highly significant for good outcome (p<0.001). Presence of preoperative endophthalmitis and postoperative RD were found to be significant for poor visual outcome (p = 0.037, 0.006 respectively).CONCLUSIONS: Many prognostic factors were recognized which aid in predicting visual outcome and identifying which patients are at highest risk for visual loss. Initial BCVA, FB entry site and location, preoperative endophthalmitis and postoperative RD were the most significant prognostic factors in predicting visual outcome.}, keywords = {Prognostic factors,intraocular foreign body,Pars Plana Vitrectomy}, url = {https://zumj.journals.ekb.eg/article_4667.html}, eprint = {https://zumj.journals.ekb.eg/article_4667_a8f3cffb20e897035fa224d4b71f0f95.pdf} } @article { author = {Zamzam, Samir and Abdel Hameed, Ali and Khalifa, Naglaa and Tolba, Sabry}, title = {ANNUAL INCIDENCE AND CLINICO-LABORATORY STUDY OF HEMOLYTIC UREMIC SYNDROME AMONG ATTENDANTS OF PEDIATRIC ZAGAZIG UNIVERSITY HOSPITAL.}, journal = {Zagazig University Medical Journal}, volume = {22}, number = {5}, pages = {1-12}, year = {2016}, publisher = {Zagazig University, Faculty of Medicine}, issn = {1110-1431}, eissn = {2357-0717}, doi = {10.21608/zumj.2016.4668}, abstract = {Background: Hemolytic uremic syndrome (HUS) is the most common cause of acute renal failure in young children. It is characterized by microangiopathic hemolytic anemia (MAHA), acute renal failure, and thrombocytopenia.Objective: This work aims to study causes, clinical presentation, annual incidence, and outcome of hemolytic uremic syndrome in children admitted to Pediatric Zagazig University Hospital.Subjects and methods: This is a descriptive study, carried out at Children hospital, faculty of medicine, Zagazig University during the period from January 2012 to January 2014.This study included 42 patients younger than 15 years with diagnosis of hemolytic uremic syndrome.Results: Most of cases were younger than 2 years of age (57%). Males (74%) were more affected than females (26%) and most of patients were detected during summer. The overall incidence in pediatric age group ( <15 years) was 1.2 per 100,000 children. Incidence was highest below 5 years old (2.69 per 100,000 children). Most of patients were presented clinically by bloody diarrhea, pallor, oliguria & anuria. Laboratory abnormalities included hemolytic anemia, thrombocytopenia, leukocytosis, hyponatremia, hypokalemia or hyperkalemia, metabolic acidosis, elevated blood urea and serum creatinine. Stool culture was positive in only 7 cases (17%).The mortality rate was 21.4%.Conclusion: Unfavorable outcome was associated with young age, anuria, intractable seizures, high WBC count more than 30,000 per mm3 ,and hyperkalemia above 5 m mol/ L.}, keywords = {Hemolytic Uremic Syndrome,Shiga-toxin,Acute kidney injury,Hemodialysis,complement,TMA,MAHA}, url = {https://zumj.journals.ekb.eg/article_4668.html}, eprint = {https://zumj.journals.ekb.eg/article_4668_908b07fdb98d0892c9841aed87993178.pdf} } @article { author = {Naguib, Mohamed and Abd-Elsalam, Mohamed and Abd El-Azeem, Amal and Yousif, Yousif}, title = {ASSOCIATION BETWEEN TRANSFORMING GROWTH FACTOR-β1 AND INTERLEUKIN-4 AND CHILDHOOD ASTHMA IN ZAGAZIG UNIVERSITY HOSPITALS}, journal = {Zagazig University Medical Journal}, volume = {22}, number = {5}, pages = {1-6}, year = {2016}, publisher = {Zagazig University, Faculty of Medicine}, issn = {1110-1431}, eissn = {2357-0717}, doi = {10.21608/zumj.2016.4669}, abstract = {Background: Interleukin (IL) 4 and transforming growth factor β1 (TGF-β1) are two key cytokines involved in a Th2-type inflammation characteristic of asthma. This type has more inflammatory cells that release cytokines which trigger broncho-constriction, mucus over-production, and remodeling of airways which augment inflammatory reactions in asthma.Objective: Our study aimed to verify the association of serum levels of both IL 4 and TGF-β1 with asthma development and further effect on its control level in Egyptian children.Subjects and methods: In this case-control study, two groups of children aged 5–15 years were recruited: first diagnosed as cases of asthma (clinically and spirometry-based); the second group of non-asthmatic children was enrolled as controls. Serum levels of total IgE, IL 4 and TGF-β1 were measured for all children. Cases were classified as controlled, partly controlled and uncontrolled (according to GINA 2008)Results: From December 2013 to Mai 2015, 156 cases and 156 controls were recruited.Serum level of serum total IgE, TGF-β1 and IL4 were significantly higher in asthmatic in comparison to non-asthmatic children. A positive correlation between serum levels of both total IgE and IL-4 and TGF-β1were noted. A higher serum level of total IgE, TGF-β1 and IL4 were noticed in children with poor asthma control.Conclusion: The data suggests that increased serum levels both TGF-β1 and IL4 in asthmatic children are associated with poor asthma control.}, keywords = {Asthma,IL4,TGF-β1}, url = {https://zumj.journals.ekb.eg/article_4669.html}, eprint = {https://zumj.journals.ekb.eg/article_4669_21763ad7d113b30c46253c296826fa6d.pdf} } @article { author = {Zeid, Nabil and Elfouly, Mahmoud and Kamel, Ahmed and Wahba, Basim and Bahman, Refaat and Sabaa, Mohamed}, title = {SEMI-OPEN RHINOPLASTY FOR APPROACHING NASAL TIP AND DORSUM}, journal = {Zagazig University Medical Journal}, volume = {22}, number = {5}, pages = {1-10}, year = {2016}, publisher = {Zagazig University, Faculty of Medicine}, issn = {1110-1431}, eissn = {2357-0717}, doi = {10.21608/zumj.2016.4670}, abstract = {Background: Rhinoplasty is one of the most complex surgical procedures in aesthetic surgery. Semi-open approach was proposed by Inchingolo et al. in 2012 with the advantages of the open technique without division of the columella.Subjects and Methods: A prospective study was conducted including fifteen patients, to whom rhinoplasty with semi-open approach was performed. Parameters used for evaluation were taken intraoperatively, one week and three months postoperatively.Results: Accessibility to tip and nasal dorsum was good, operative time was relatively long. Most of cases had moderate edema immediately and 1 week postoperatively. Many cases continued to have residual edema after 3 months follow up.Conclusion: Semi-open approach allows good exposure to tip and dorsum without dividing the columella which can be used in cases with nasal dorsum and tip deformities. However, it is time consuming with prolonged postoperative edema in many cases.}, keywords = {Rhinoplasty,Rhinoplasty approaches,Semi-open rhinoplasty,Closed rhinoplasty with open advantages,external marginal approach}, url = {https://zumj.journals.ekb.eg/article_4670.html}, eprint = {https://zumj.journals.ekb.eg/article_4670_f9784ac3a5874211f3399a7eed3cdcc2.pdf} }