Glucose-6-Phosphate Dehydrogenase Deficiency among Newborns in Sana’a City, Yemen

Nassar, Mogahid; Hudna, Ahmed S; Alhaj, Ali; Alqubaty, Abdulhabib; Alqahtani, Talal

doi:10.21608/zumj.2020.32403.1876

Glucose-6-Phosphate Dehydrogenase Deficiency among Newborns in Sana’a City, Yemen

Document Type : Original Article

Authors

¹ Department of Pathology, Faculty of Medicine and Health Sciences, University of Sciences and Technology, Sana’a, Yemen

² Department of Pediatrics, Faculty of Medicine and Health Sciences, University of Sciences and Technology, Sana’a, Yemen

³ Department of Biochemistry, Faculty of Medicine and Health Sciences, University of Science and Technology, Sana&#039;a, Yemen

⁴ Department of Biochemistry, Faculty of Medicine and Health Sciences, University of Sciences and Technology, Sana’a, Yemen

⁵ Department of Microbiology, Faculty of Medicine and Health Sciences, University of Sciences and Technology, Sana’a, Yemen

10.21608/zumj.2020.32403.1876

Abstract

Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common inborn enzymatic defect in the world. Determining the prevalence of G6PD deficiency is an essential step towards evaluating its impact on the health of a population. Therefore, this study aimed to determine the prevalence and factors associated with G6PD deficiency among newborns in Sana’a city, Yemen.
Subjects and methods: This cross-sectional study included 397 newborns from eight public and private hospitals in Sana’a city in the period from January to March 2020. Data about gender and the factors possibly associated with G6PD deficiency were collected using a pre-designed questionnaire. G6PD deficiency was qualitatively detected in fresh blood using rapid diagnostic tests (RDTs). Data were analyzed using SPSS software, and differences were considered statistically significant at p-value

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