Comparative Study Between Modified Ross Score and Pediatric Heart Failure Index using pro-BNP in Quantifying Severity of Heart Failure in Pediatrics

Document Type : Original Article

Authors

1 Department of pediatrics, faculty of medicine, zagazig university

2 department of pediatrics, faculty of medicine, zagazig university

3 Department of Clinical Pathology, Faculty of Medicine, Zagazig University

4 Department of pediatrics , faculty of medicine, zagazig university

Abstract

Background: Modified Ross Score and Pediatric Heart Failure Index (PHFI) are a standardized scoring systems to evaluate heart failure in the pediatric population which are useful since it may facilitate treatment appraisal and outcome analysis. The present work aimed to evaluate the specificity and sensitivity of Modified Ross and Paediatric Heart Failure Index for quantifying severity of HF using pro-BNP.
Methods: A comparative study was conducted on 48 patients (26 males and 22 females) with congestive heart failure whose ages ranged from 4 months till 2 years, All having the inclusion criterion of CHF. All children were subjected to full history taking, physical examination, and classification of clinical severity of CHF in cases according to Modified Ross Score, PHFI Score, X- ray chest and heart, ECG, echocardiography and laboratory investigations. The laboratory investigations were a routine such as: CBC and a special investigation which is serum level of NT-proBNP.
Results: our study showed a statistically significant positive correlation between M-ROSS scale and pro-BNP levels. There was a high statistically significant positive correlation between PHFI diagnostic scale and pro-BNP level and HR among studied patients. PHFI score was positively correlated with the modified Ross score According to modified Ross score. BOTH scores showed high ability to detect severe cases,as PHFI accuracy reaching up to 94.5% , while accuracy of M-Ross was 90.5% .
Conclusion: The study revealed that PHFI was more significant correlation than M-ROSS with NT-proBNP, so PHFI seems more accurate and sensitive to severe cases than M-ROSS.

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