Can Mean Platelet Volume, Platelet /Lymphocyte ratio and Neutrophil /Lymphocyte ratio predict severity of Coronary Artery calcification assessed by Multidetector CT Coronary Angiography?

Seaoud, Elshaimaa A; Selim, Nada Mahmoud; Esherbiny, Islam Abdelmoneem; Mostafa, Ahmed Magdy

doi:10.21608/zumj.2020.38884.1920

Can Mean Platelet Volume, Platelet /Lymphocyte ratio and Neutrophil /Lymphocyte ratio predict severity of Coronary Artery calcification assessed by Multidetector CT Coronary Angiography?

Document Type : Original Article

Authors

¹ Department of Cardiology ,Faculty of Medicine,Zagazig University,Zagazig,44159,Egypt

² Kobry Elkoba Military Hospital,Cairo,Egypt ,

³ Division of cardiovascular medicine, faculty of Human Medicine , Zagazig University

⁴ Kobry Elkoba Military Hospital ,Cairo ,Egypt

10.21608/zumj.2020.38884.1920

Abstract

1-Abstract

Background and aim: Increasing attention is being paid to the role of inflammatory markers and their relationship to the severity of coronary artery disease. Our aim was to prove that a 3 simple CBC indices (platelet / lymphocyte ratio (PLR) , neutrophil / lymphocyte ratio (NLR) and mean platelet volume (MPV)) can help assess severity of coronary artery calcium using multi detector CT (MDCT).
Methods: 70 male patients prospectively undergoing CT coronary angiography (CTCA) for chest pain or multiple risk factors for coronary artery disease (CAD) have been registered. Blood samples for complete blood count, differential leucocyte count and full lipid profile were collected.
Results: There was a significant negative correlation between NLR ratio and coronary artery calcium score (CACs) (P-value

Keywords