The Frequency of Tumor Necrosis Factor-alpha Gene Polymorphism in Patients with Chronic Immune Thrombocytopenia.

Document Type : Original Article

Authors

1 pediatric department faculty of medicine zagazig university

2 pediatric department,faculty of medicine,zagazig university

3 Medical Biochemistry, Faculty of Medicine, Zagazig University, Egypt

Abstract

Background: The aim of this study was to reveal the frequency of Necrosis Factor _Alpha Gene Polymorphism in evaluation of severity and outcome of chronic immune thrombocytopenia in pediatric department of Zagazig University hospitals.
Methods: We conduct a retrospective case control on 40 children diagnosed with chronic ITP and 40 age and sex healthy matched subjects as a control recruited from outpatient hematology clinic Faculty of Medicine, Zagazig University.
Results: We found a highly significant difference between ITP group and control group as regarding TNF-α alleles where A allele was expressed in 43.7% of cases versus 17.5% 0f control, P value

Keywords

Main Subjects

Zagazig University Medical Journal
Volume 29, Issue 1
January 2023
Pages 155-160

Files

Share

How to cite

Statistics