Neutrophil to lymphocyte ratio (NLR), and platelet to lymphocyte ratio(PLR) as a predictor of stroke in patients with COVID-19

Document Type : Original Article

Authors

1 faculty of medicine,zagazig universioty

2 Neurology dept., Faculty of medicine, Zagazig University, Zagazig, Egypt

3 faculty of medicine, zagazig university

Abstract

Background: coronavirus disease 2019 (COVID-19), is documented as an emerging global pandemic, representing one of the leading causes of morbidity and mortality worldwide. Stroke is arguably the most important complication of COVID-19. It may be presumed that NLR and PLR could be used as biomarkers of endothelial dysfunction in many diseases including stroke. This study aimed to explore the role of NLR and PLR as predictive markers of stroke in patients with COVID-19.
Methods: 392 confirmed COVID -19 subjects retrospectively analyzed. Among enrolled COVID-19 patients, only 24 patients had a stroke (ischemic stroke= 21 and non-ischemic stroke, n=3). Clinical, laboratory, and radiological parameters were investigated.
Results: Among Covid -19 ,24 (6.1%) had acute ischemic stroke, 3 (0.76%) had non-ischemic stroke. results show that PLR was 271.2±161.4 and NLR was 5.96±2.4 in COVID -19 patients (n=392) There was a significant difference between studied groups as regard NLR, Covid -19 patients without stroke,(5.7±3.24), ischemic stroke, (9.2±3.32) and non-ischemic stroke, (8.29±3.12), p < /p>

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Zagazig University Medical Journal
Volume 28, Issue 1
January 2022
Pages 151-162

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