Are you in a poor country; hyper-thermic intra-peritoneal chemotherapy is still in reach: A clinical trial.

Document Type : Original Article

Authors

1 General surgery, faculty of medicine, Zagazig university, Zagazig, Egypt

2 General Surgery Department, Faculty of Medicine, Zagazig University, Egypt

3 Surgery

Abstract

Abstract
Background: hyper-thermic intra-peritoneal chemotherapy (HIPEC) is established now as a considerably effective treatment method for peritoneal surface malignancy after optimal cyto-reduction. The obstacle faced by poor places is the high cost of the standard machines and their consumable kit per procedure. This opened the door for the trials of innovating cheaper ones as the one we deigned.
Methods: We evaluated the cost of the machine of our design, its expenses per procedure as well as the success of achieving the target temperature and good flow rate, safety aspects, technical failures and the technical support required. The comparison with standard machines was based on the manufacturer information and published reports and not on personal use.
Results: Form 2014 to 2017; we performed HIPEC (Coliseum technique) for patients using the machine of our design. Flow rate was 2 L/min and target temperature between 41 and 43 °C could be achieved in all cases. There were no technical failures and there was no safety issue recorded. Chemotherapy costs were not included and independent from the devices used. Cost of consumable kit was 110 USD/procedure, as compared to 1800 to 3500 USD/procedure for commercially available products. The cost for standard machines is between 40,000 and 135,000 USD.
Conclusions: Our design in HIPEC machine was efficient, easy to use, with no recorded complications from technical accidents or failure.

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Zagazig University Medical Journal
Volume 28, Issue 6
November 2022
Pages 1398-1406

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