Background: COVID-19 has affected millions of people worldwide. To date, efforts made to develop antiviral strategies for the treatment of COVID-19 remain underway. Respiratory viral infections predispose to co-infections which lead to increased disease severity and mortality. This study aimed to determine COVID-19 bacterial co-infection incidence and assess the severity and outcome among patients in Zagazig University quarantine ICUs. Patients and methods: This prospective cohort study was carried out on moderate and severe COVID-19 patients admitted to Zagazig University quarantine intensive care units , full history taken ,complete physical examination and vital signs with laboratory investigations ,bacterial co-infection assessment (within 48 hrs of admission ) in form of persisting fever or leucocytosis (neutrophilia) and high procalcitonin with blood or sputum cultures, follow up the patients till discharge or death. Results: Among 180 studied COVID-19 patients there was 21.1% of them had bacterial co-infection while 78.9 % were without bacterial co-infection, there was 8.9% with positive blood cultures and 16.1 with positive sputum cultures. There was significantly higher percent of severity, CPAP need and death rate among patients with bacterial co-infection ,there was statistically significant difference regarding duration of ICU stay with higher median in COVID-19 without bacterial co-infection. Conclusion: The incidence of COVID-19 bacterial co-infection among patients in Zagazig University quarantine ICUs was 21.1% with Klebsiella organism the most causative organism and there was significantly higher percent of severity and death rate among COVID-19 patients with bacterial co-infection.
Ahmed, E., Samra, S., Mohammed, M., & Zake, L. (2022). Bacterial Co-Infection Among Corona Virus Disease-19 Patients in Zagazig University Quarantine Intensive Care Units. Zagazig University Medical Journal, 28(5), 1147-1155. doi: 10.21608/zumj.2022.129209.2535
MLA
Esam Albashir Ahmed; Saad Samra; Mohammed Fawzy Mohammed; Lamiaa Gaber Zake. "Bacterial Co-Infection Among Corona Virus Disease-19 Patients in Zagazig University Quarantine Intensive Care Units". Zagazig University Medical Journal, 28, 5, 2022, 1147-1155. doi: 10.21608/zumj.2022.129209.2535
HARVARD
Ahmed, E., Samra, S., Mohammed, M., Zake, L. (2022). 'Bacterial Co-Infection Among Corona Virus Disease-19 Patients in Zagazig University Quarantine Intensive Care Units', Zagazig University Medical Journal, 28(5), pp. 1147-1155. doi: 10.21608/zumj.2022.129209.2535
VANCOUVER
Ahmed, E., Samra, S., Mohammed, M., Zake, L. Bacterial Co-Infection Among Corona Virus Disease-19 Patients in Zagazig University Quarantine Intensive Care Units. Zagazig University Medical Journal, 2022; 28(5): 1147-1155. doi: 10.21608/zumj.2022.129209.2535
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