Document Type : Original Article
Authors
1
Department of Internal Medicine, Faculty of Medicine, University of Science and Technology.
2
Department of Department of Internal Medicine, Faculty of Medicine, University of Science and Technology
3
Department of Internal Medicine, Faculty of Medicine, Omdurman Islamic University. abdelsalamnail@yahoo.com
4
Department of Internal Medicine, Faculty of Medicine, Sudan International University.
5
Department of Department of Internal Medicine, Faculty of Medicine, University of Science and Technology. Altilib19@gmail.com
6
Department of Department of Internal Medicine, Faculty of Medicine, University of Science and Technology.
7
Department of Physiology, Faculty of Medicine, National University-Sudan , Department of Physiology, RAK College of Medical Sciences, RAK Medical and Health Sciences University, Ras Al-Khaimah, UAE.
8
Department of Physiology, Faculty of Medicine, The National Ribat University, Khartoum, Sudan
Abstract
Background: Leishmaniasis is an endemic disease in Sudan that caused by Leishmania spp. Several studies suggest neurological manifestations in visceral leishmaniasis, such as burning sensation, and weakness.
Objective: This study was aimed to assess the frequency of the neurological manifestations in Visceral Leishmaniasis.
Method: This is a descriptive, prospective cohort study, was conducted in The Tropical Teaching Hospital – Khartoum for one-year duration. A pretested questionnaire contained the study variables was conducted, and laboratory tests were done. SPSS v 26.0 was used to analyze the data.
Results: Forty four percent of total patients (22/50) were symptomatic.Peripheral neuropathy was elicited in 60% (30/50), Numbness has been the most common feature 56.6% (17/30), and Weakness 26.6% (8/30) all were Axonal damage. Sensorimotor neuropathy was exhibited in 70% (21/30), pure motor neuropathy in 26.7% (8/30). Polyneuropathy was encountered in 46.6% (14/30), poly-radiculopathy in 20% (6/30) along with 23.3% (7/30) as mononeuropathy.
Conclusion: peripheral neuropathy was developed in patients with visceral leishmaniasis, frequent occurrence of subclinical neurological manifestations is higher than reported.
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