One Month Major Adverse Cardiac Events in Postmenopausal Females with Acute Coronary Syndromes; Conservative versus Invasive Management

Document Type : Original Article

Authors

Cardiology Department, Faculty of Medicine, Zagazig University

Abstract

Background: Myocardial infarction (MI), in particular, and cardiovascular disease were long believed to be exclusively male conditions. Thankfully, there is growing recognition in both the medical literature and the general public that heart disease is the leading cause of mortality for women and that cardiovascular illness is gender insensitive. This study aimed to compare MACE among post-menopausal females admitted to CCU with acute coronary syndromes. Patients and Methods: The current study included 144 female patients with mean age 59.32 years. Mean BMI =26.85 kg/m2. Positive family history 78.5%. AS regard comorbidity, 41.7%, 48.6%, and 41.7% had comorbid diabetes, hypertension and dyslipidemia. STEMI was (55.6%) of patients in which 10 cases received thrombolytic therapy and 70 cases admitted to PCI. Non-STEMI and unstable angina patients were (44.4%) in which 20 cases admitted to PCI and 44 cases received medical treatment. Results: we enrolled 144 post-menopausal patients presented with acute coronary syndromes and in comparison between the conservative and invasive methods of treatment in each group of (STEMI) and (Non-STEMI) and following-up the patients one month for MACE, the MACE was higher in group of invasive arm than conservative arm with (37.8% versus 18.5 %) respectively, Heart failure (7.4%, 21.1%), Serious arrhythmia (14.8%, 26.7%) Reinfraction (6.7% 3.7%) Mortality (6%, 0%). Conclusion: According to the findings of our research, it is possible to conclude, "Compared to the non-invasive approach, the invasive option is associated with worse outcomes in patients with NON-STEMI. The non-invasive strategy is associated with better outcomes than the invasive option

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