Correlation of Epicardial Fat Thickness and Severity of Coronary Plaque ‎Lesion Using Echocardiography and Cardiac Multidetector Computed ‎Tomography ‎

Document Type : Original Article

Authors

1 department of Cardiology and Vascular Diseases, Faulty of Medicine, Zagazig University

2 cardiology department,zagazig Zagazig University

3 Cardiology Department, Faculty of Medicine , Zagazig University, Egypt

4 Cardiology Department, Faculty of Medicine, Zagazig University

5 Cardiology Department, Faculty of Medicine, Zagazig University, Egypt.

Abstract

Background: Epicardial fat considered a part of visceral fat depot; it surrounds the myocardium ‎just underneath the visceral pericardium where it has close proximity to the coronaries. ‎Researches proof that epicardial adipose tissue is biologically active and so may had a ‎significant role in the occurrence and severity of atherosclerotic CAD. Advances in ‎cardiovascular imaging techniques make echocardiography and MDCT accurate enough to ‎assess both EFT and EFV respectively. Patients and Methods: One hundred participants were ‎recruited in this cross sectional study from January to December 2022. Patients were referred to ‎Kobri El Kobba Military Hospital with suspected CAD for multi-slice CT angiography. ‎

Results: Patients were classified into two groups according to the results of the CT coronary ‎angiography; group (I) with significant CAD, 82 cases and group (II) without significant CAD, ‎‎18 cases. There was a statistically significant difference between group I and group II regarding ‎BMI, HTN, DM, total cholesterol, LDL, HDL, triglycerides, LDL/HDL ratio, EF (%), RSWMA, ‎Epicardial Fat volume (EFV) measured by MDCT and EFT measured by Echocardiography. ‎There was no statistically significant difference between the subgroups Ia, Ib and Ic regarding ‎EFT measured by Echocardiography. EFV measured by MDCT is the most statistically ‎significant predictor for severe CAD or multi-vessel disease. Conclusion: Epicardial fat depot ‎was significantly associated with plaque development and vulnerability where EFT and EFV ‎showed high values and were closely related to CAD presence and severity.‎

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Zagazig University Medical Journal

Articles in Press, Accepted Manuscript
Available Online from 03 December 2023

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