Impact of Use Of Local Phenytoin On postoperative outcomes of pediatric tonsillectomy

Document Type : Original Article

Authors

1 Otorhinolaryngology, faculty of medicine, Zagazig university , Egypt

2 otorhinolaryngology faculty of medicine, Zagzig university

Abstract

objective

To assess the short-term results of tonsillectomy alone versus tonsillectomy with local phenytoin with regard to postoperative pain, analgesia, bleeding and appetite.

The study included in all 107 pediatric tonsillectomy patients; seven patients were excluded due to incomplete follow-up, only 100 patients completed follow up (60% female, 40% male, with age of (4–11 years) randomly chosen for tonsillectomy alone ( group1 or TA ; n = 50) and tonsillectomy with local phenytoin therapy( use)

(TPHT group, n = 50) . Patient characteristics such as age ,sex, and postoperative visual analogue scale (VAS) pain scores (2 hours postoperatively and first 10 days), appetite scores (first 7 days), and analgesia requirement (first 10 days) with documentation of bleeding complications.

Results From the third postoperative day, there was a noticeable decline in pain scores, which reached 0.0 ± 0.0.and on Day 10, it was 0.49± 0.79 in the TPHT and TA groups, respectively (p < 0.001 for each). Comparing the TPHT group to the TA group, there were significant differences in pain and appetite scores from Day 1 to Day 10, as well as a decreased need for analgesia from Day 1 to Day 10. Additionally, there were few bleeding complications



In conclusion, this study of pediatric tonsillectomy patients proved effectiveness of tonsillectomy with local phenytoin (use) over tonsillectomy without local phenytoin therapy(use)

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Zagazig University Medical Journal
Volume 30, Issue 1.4
May and June 2024
Pages 111-117

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