Comparison of Fagotti’s index and Sugarbaker’s peritoneal cancer index (PCI) in Predicting Resectability in advanced ovarian cancer

Document Type : Original Article

Authors

1 Obstetrics and Gynecology Department, Faculty of Medicine, Zagazig University

2 Obstetrics and Gynecology Department, Faculty of Medicine, Zagazig university, Egypt

Abstract

Background: Peritoneal carcinomatosis is a condition manifests in advanced stages of ovarian cancer. The primary determinants of total debulking are the disease's volume and distribution. The procedure known as diagnostic laparoscopy makes it possible to assess the illness. The purpose of this study is to evaluate the diagnostic accuracy of two laparoscopic scores—the Fagotti's index and Sugarbaker's peritoneal cancer index (PCI)—in order to reduce the number of needless laparotomies and identify patients who should get neoadjuvant treatment. Methods: This prospective cohort study occurred in Obstetrics and Gynecology Department, Zagazig Gyneoncology Unit (ZGOU), Faculty of Medicine, Zagazig University, Egypt on patients with diagnosis of peritoneal carcinomatosis in advanced ovarian cancer. Fagotti’s index and Sugarbaker’s peritoneal cancer index were assessed in all cases.

Results: PCI score achieved higher area under the curve (AUC) of 0.920 while Fagotti score had an AUC of 0.823. The PCI score cut-off level for the prediction of resectability was (≥ 15 ) which had a sensitivity of 80% and a specificity of 80%, predictive value for positive (PVP) = (66.7%), predictive value for negative (PVN) = (88.9%), and (80%) accuracy.

Conclusion: Both Sugarbaker’s (PCI ) and Fagotti ’s index are reliable and accurate indices in predicting resectability in advanced ovarian malignancy with Sugarbaker’s (PCI ) being more specific.

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Zagazig University Medical Journal
Volume 30, Issue 9
December 2024
Pages 4594-4607

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