Overview on Klebsiella Pneumoniae Resistance to Antibiotics

Document Type : Review Articles

Authors

1 Medical Microbiology and Immunology Department, Faculty of Medicine, Zagazig University

2 Department of Chest diseases, Faculty of Medicine, Zagazig University, Egypt

Abstract

Background: Klebsiella pneumoniae is an opportunistic bacteria linked to a range of infections. Klebsiella pneumoniae is a gram-negative bacterium that can colonize, invade, and cause infections in several parts of human body. The rise of hypervirulent pathotypes, its capacity to elude the immune system, and rising antibiotic resistance have made it a significant challenge in the medical industry. In this study, virulence factor gene presence and the antibiotic resistance mechaisms that have been used by k.pneumoniae to tolerate used antibiotics were reviewed.

Conclusion: K. pneumoniae is known to be a pathogenic factor that thought to be a cause of several infection such as pneumonia, liver abscess, UTI and GIT colonization. Being also resistant to many antibiotics this makes many people sufferring diseases that caused by k.pneumoniae and urges us to try to understand and study virulence factors and different mechanisms of resistance that still till now not completly obvious In order to find ways of treatment that will alleviate sufferring of people with diseases.

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Zagazig University Medical Journal
Volume 31, Issue 1
January 2025
Pages 264-270

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