Role of Platelet Derivatives in Regenerative Aesthetics and Platelet Rich Plasma in Managing Striae Distensae

Document Type : Review Articles

Authors

1 MBBCH, Faculty of Medicine, Zagazig University

2 Assistant Professor of Dermatology, Venereology, and Andrology Department, Faculty of Medicine, Zagazig university

3 Lecturer of Dermatology, Venereology, and Andrology Department, Faculty of Medicine, Zagazig university

Abstract

Background: Although platelet-derived bioproducts have long had widespread medical usage, there has been a dramatic uptick in their use for cosmetic and dermatological purposes in recent years. Important growth factors obtained from peripheral blood are stimulated to proliferate blood vessels by products like platelet-rich plasma (PRP) and platelet-rich fibrin (PRF). The fibrin polymerization process is aided by PRP and PRF in particular, resulting in a strong structure that can store many growth factors. Tissue regeneration is aided by these substances, which stimulate cell migration, differentiation, and proliferation as well as the creation of collagen and elastin. Aesthetic medicine makes use of these effects for a variety of reasons, such as restoring hair, treating scars, managing striae, and promoting wound healing. In addition, microneedling, laser therapy, and radiofrequency are just a few examples of how these biological products might complement conventional therapeutic methods. We aimed to present a summary of Role of platelet derivatives in regenerative aesthetics and platelet rich plasma in managing striae distensae.

Conclusion: While platelet-rich plasma and its derivatives show great potential as non-invasive solutions to a range of cosmetic issues, there are still many unknowns and obstacles to overcome before they can be widely used. The growth factors included in PRP have a therapeutic significance in striae distensae management because they promote angiogenesis and upregulate collagen synthesis, two processes critical to tissue repair and remodeling.

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Zagazig University Medical Journal
Volume 31, Issue 2
February 2025
Pages 739-748

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