Document Type : Review Articles
Authors
1
Assistant Professor of Dermatology, Venereology and Andrology Faculty of Medicine, Zagazig University, Member of Interactive Dermatology Research Group, Cairo, Egypt.
2
Assistant Professor of Dermatology, Venereology and Andrology Faculty of Medicine, Zagazig University
3
Dermatology, Venereology and Andrology Department, Faculty of Medicine, Zagazig university, Egypt
Abstract
Background: Cutaneous warts are a proliferative condition caused by human papillomavirus (HPV) infecting keratinocytes. These viral warts are widespread, affecting 7–12% of the population. HPV, a double-stranded DNA virus, encompasses over 200 identified types, broadly classified into high-risk and low-risk groups based on their potential to cause cancer. The virus’s life cycle is intricately tied to epithelial cell growth and differentiation. Treating persistent warts has long posed a significant challenge for dermatologists due to their tendency to recur. While warts can be managed, eliminating the HPV virus entirely remains unattainable. Numerous treatment methods are currently available, including surgical removal, cryotherapy, pharmacological approaches (e.g., salicylic acid, trichloroacetic acid), and immunotherapies (e.g., Candida antigen and HPV vaccination). Laser therapy has emerged as a promising option for stubborn warts, with several types being evaluated, such as carbon dioxide (CO2), pulsed dye (PDL), erbium:yttrium-aluminum-garnet (Er:YAG), neodymium:YAG (Nd:YAG), and Alexandrite lasers, as well as their combinations. Conclusion: Laser treatments have been shown to be both safe and effective, often yielding higher success rates compared to traditional methods.
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