Effect of Intravenous Magnesium Sulphate, Lidocaine or Dexamethasone on Incidence and Severity of Laryngospasm and Postoperative Pain in Pediatrics Undergoing Adenotonsillectomy

Abdalla Othman, Ali Ibrahim; Attia, Zainab Mostafa; Abaza, Kamelia Ahmed; Tawfic, Ahmed M.

doi:10.21608/zumj.2025.366246.3865

Effect of Intravenous Magnesium Sulphate, Lidocaine or Dexamethasone on Incidence and Severity of Laryngospasm and Postoperative Pain in Pediatrics Undergoing Adenotonsillectomy

Document Type : Original Article

Authors

¹ Anesthesia, Intensive Care and Pain Management Department, Faculty of Medicine, Tripoli University, Libya

² Professor of Anesthesia, Intensive Care and Pain Management, Faculty of Medicine, Zagazig University, Egypt

³ Lecturer of Anesthesia, Intensive Care and Pain Management, Faculty of Medicine, Zagazig University, Egypt

10.21608/zumj.2025.366246.3865

Abstract

Background: Post-extubation laryngospasm is a common and serious complication in Pediatrics Undergoing Adenotonsillectomy. This study aimed to evaluate and compare the effect of intravenous magnesium sulphate, lidocaine or dexamethasone on the incidence and severity of laryngospasm and postoperative pain in pediatrics undergoing adenotonsillectomy. Methods: Included Seventy-Five children undergoing adenotonsillectomy were divided into three groups, each of 25 children. Group M; received an intravenous infusion of 15mg/kg 10% magnesium sulfate in 50ml of 0.9% sodium chloride over 10min. Group L; received an intravenous infusion of 1 mg/kg 2% lidocaine in 50ml of 0.9% sodium chloride over 10min. Group D; received an intravenous infusion dexamethasone 0.5mg/kg in 50ml of 0.9% sodium chloride over 10min. Results: There was a significant difference among the studied groups regarding recovery time that was higher in group I than group II and III. None of patients any complications, regarding incidence of laryngospasm after extubation at 1, 5, 10 and 15 minutes, which had no statistically significant differences. Conclusion: that intravenous magnesium sulfate is more effective than intravenous lidocaine and dexamethasone in reducing the incidence and severity of laryngospasm, however, it is associated with a relatively prolonged recovery time compared with lidocaine and dexamethasone.

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