Diabetic Population (Type 1 Versus Type 2) Characteristics and Severity of Coronary Artery Disease in Chronic Coronary Syndrome

Document Type : Original Article

Authors

1 Lecturer of Cardiology Department, Faculty of Medicine, Zagazig university, Egypt

2 Assistant Professor of Cardiology Department, Faculty of Medicine, Zagazig university, Egypt

3 Department of Cardiology, Faculty of Medicine, Sebha University-Libya

4 Professor of Cardiology Department, Faculty of Medicine, Zagazig university, Egypt

Abstract

Background: Heart disease is the primary cause of death for diabetics. Obesity, systemic hypertension, and hyperlipidemia factors frequently found in diabetic patients have been connected to an increased risk of coronary artery disease (CAD). In order to improve care and lower CAD in diabetic individuals with chronic coronary syndrome (CCS), this study aims to quantify the severity of CAD. Methods: out of 140 diabetic patients with chronic coronary syndrome,70 being type 1diabetes mellitus (T1DM) and 70 are type 2 diabetes mellitus (T2DM), undergone percutaneous coronary angiography (PCI) to evaluate the severity of coronary artery by using syntax and Gensini scores. Results: type 2 diabetes mellitus (DM) were older, 82.9% were males (p<0.001), had higher systolic (150±19.3vs 131.8±14.8) p<0.001 and diastolic (86.4 ± vs 82.1 ± 7.14) p=0.003 blood pressure compared to type 1 DM also, T2DM had higher levels of triglycerides (99.2±27vs 87.1±14.9) p=0.003, higher lower density lipoprotein (LDL) (172.1±32.3vs 158.2±21.7) p=0.001, and poor glycemic control (34.3%vs 11.4%) p=0.002 compared to T1DM Type 2 diabetes mellitus revealed higher Syntax (p<0.001) and Gensini (p<0.001) scores in comparison to type 1 diabetes mellitus. Conclusion: Type 2 diabetes mellitus patients had more sever and a complex coronary artery disease than those with type1 diabetes mellitus.

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