Correlation between Residual Kidney Function, Quality of Life and Cognitive Function in Haemodialysis Patients

Document Type : Original Article

Authors

1 Internal Medicine Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt

2 Internal Medicine Department, Faculty of Medicine, Zagazig University, Sharkia Egypt

Abstract

Background: Patients undergoing permanent renal replacement therapy may benefit greatly from residual kidney function (RKF), which is demonstrated by improved biochemical parameter management. Cognitive function and quality of life (QOL) are frequently compromised in hemodialysis patients. Therefore, our goal was to evaluate residual renal function and clarify how it affected the quality of life and cognitive function of ESRD patients receiving regular hemodialysis.

Methods: This cross-sectional observational case control study was carried out on 56 ESRD patients on haemodialysis for at least six months. Patients were divided into two: Group 1 (Study group): patient with urine volume >100 mg per day and group 2 (control group): Patient with urine volume < 100 mg per day.

Results: Group 2 had a considerably larger list of symptoms, role constraints brought on by physical health issues, pain, and role limitations brought on by emotional health issues than group 1. Group 1 outperformed Group 2 in terms of cognitive function, sleep, general health, physical functioning, social function, energy weariness, and physical composite score. Visuospatial executive, naming, attention, abstraction, delayed recall, orientation, memory, and the overall MoCA score were all positively connected with RKF. Other factors that were positively correlated included patient satisfaction, physical functioning, role limitations brought on by physical health issues, pain, general health, role limitations brought on by emotional health issues, social function, energy fatigue, and physical and mental composite scores.

Conclusions: RKF in hemodialysis patients is associated with better clinical outcomes, quality of life, and cognitive function.

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Zagazig University Medical Journal
Volume 31, Issue 8
August 2025
Pages 4209-4217

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