THE ROLE OF POLYVINYL ALCOHOL AND MITOMYCIN C IN PREVENTION OF SYNECHAIE AFTER ENDOSCOPIC SINUS SURGERY

Document Type : Original Article

Authors

1 Otorhinolaryngology Department, Faculty Of Medicine, zagazig university

2 Otorhinolaryngology Department, Faculty Of Medicine , zagazig university

Abstract

Background: Functional endoscopic sinus surgery (FESS) is a minimally invasive surgical procedure that opens up the sinus air cells and sinus ostia through endoscopic surgery, and has two main goals: maximum preservation of mucosa and secure communication between the nasal cavity and the paranasal sinus via natural channels .Despite the established efficacy of FESS for the treatment of chronic rhinosinusitis (CRS), recurrent symptoms developed in 1 - 36% of patients, necessitating revision surgery.
Methods: This is a prospective double blinded randomized study which was carried out on 30 patients (13 female and 17 male) ranging in age from 18 to 60 years with bilateral CRS with or without sinonasal polyposis. Duration of symptoms ranged from 5 months to 5 years. ESS had been done for all patients. The study period was from February 2017 to April 2018. All cases were selected from the outpatient clinic of Otorhinolaryngology department in Zagazig University hospital according to the inclusion criteria.
Results: Our results shows statistically insignificant difference between PVA packing side and traditional packing side, statistically significant difference between MMC packing side and traditional packing side and statistically insignificant difference between MMC side and PVA side for postoperative complication .
Conclusion: In patients undergoing ESS, using of MMC can significantly reduce the risk of synechiae formation more than using PVA and traditional packs.

Keywords

Zagazig University Medical Journal
Volume 28, Issue 2
March 2022
Pages 181-190

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