Role of central venous to arterial carbon dioxide tension difference in hemodynamic optimization and its correlation with cardiac index after major abdominal surgery:

Hassan, Amr Ali; Sawan, Zainab Hamed; Gamil, Neven Mohamed; Salim, Dina A.

doi:10.21608/zumj.2020.23641.1728

Role of central venous to arterial carbon dioxide tension difference in hemodynamic optimization and its correlation with cardiac index after major abdominal surgery: "A prospective observational study"

Document Type : Original Article

Authors

¹ Anesthesia and Surgical intensive care department, Faculty of medicine, Zagazig University, Egypt

² Anesthesia department, Faculty of Medicine, Zagazig University

³ Anaesthesia and Surgical ICU department, Faculty of Medicine, Zagazig University, Zagazig, Egypt

⁴ anesthesia, faculity of medicine, zagazig university, egypt

10.21608/zumj.2020.23641.1728

Abstract

Introduction: The use of central venous to arterial carbon dioxide tension difference (∆PCO2) as a marker of overall perfusion even when macro-circulatory indicators appear to be normal is gaining ongoing support. This study aimed to assess the utility of ∆PCO2 in hemodynamic optimization in patients following major abdominal surgeries.
Patients and methods: For this prospective observational study, 50 consecutive patients admitted to the ICU following major abdominal surgeries, with ScvO2≥70% and fitting our inclusion criteria were included once admitted (T0). Patients were separated into low ∆PCO2 group (n=27) and high ∆PCO2 group (n=23) according to a threshold of 6 mmHg at T0. Demographics, SAPS II and SOFA scores were recorded at T0, while hemodynamic and biological parameters including CI, ∆PCO2, ScvO2% and lactate level were recorded at T0, T6, T12 and T24.
Results: At T0, there was a significant difference between the high and the low ∆PCO2 patients for ∆PCO2 (8.7±2.7vs4.1±1.5mmHg, P

Keywords

Main Subjects