Document Type : Original Article
Authors
1
Family Medicine department, Faculty of Medicine, Zagazig university, Egypt
2
Internal Medicine department, zagazig university, zagazig
Abstract
Background: Diabetic dyslipidemia is characterized by elevated fasting, postprandial triglycerides (TGs), low high-density lipoprotein (HDL), and elevated low-density lipoprotein (LDL). This study aimed at assessing frequency of dyslipidemia among patients with diabetes, identifying risk factors for potential dyslipidemia and defining its relation with diabetic foot risk.
Methods: A cross-sectional study involved 345 patients with type 2 diabetes mellitus attending Diabetes outpatient clinic, Zagazig University hospital from March to September 2019. The studied patients underwent history taking, physical examination emphasizing on foot examination and laboratory investigations including lipid profile, and glycosylated hemoglobin (HbA1c).
Results: Mean patients’ age was 50.34 years. Male constituted 58.3%. About 86% , 42%, 44.1% had middle social class, comorbid hypertension, and uncontrolled diabetes respectively. Dyslipidemia prevailed in 41.4%. About 20.3% had low diabetic foot risk. There were significant relation between occurrence of dyslipidemia and all of diabetes control, cigarette smoking, comorbid hypertension, body weight, BMI, fasting blood glucose (FBG), and diabetic foot risk. Increasing body weight non-significantly elevated risk of dyslipidemia by about one fold. Rising duration of diabetes, fasting blood glucose, uncontrolled diabetes, and presence of comorbid hypertension significantly increased that risk by about one, one, five, two and seven folds respectively. Dyslipidemia significantly increased risk of intermediate, high and very high risk for diabetic foot by three, 6.15 and 6.42 folds respectively.
Conclusion: Dyslipidemia was prevalent in diabetic patients. Increasing duration of diabetes, (FBG), uncontrolled diabetes, comorbid hypertension were significant risk factor for dyslipidemia. Dyslipidemia significantly increased diabetic foot risk.
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